Thursday, June 24, 2010

Valtrex & Valcyte for CFS

 Thought I'd post this now, or else I'll probably forget to otherwise. Yes, yet another study on another "wonder drug". Vacyclovir/valacyclovir/Valtrex for EBV-infected patients. But still an interesting read...

(Edit: The study applies to people who test positive for all herpesvirus subgroups (EBV, HCMV, HHV6))

• The Group A herpesvirus CFS patients (no coinfections) returned to a near-normal to normal life (P = 0.0001). [Probability of result occuring by chance 1 in 10,000.]
-  The long-term EIPS value increased (primary endpoint, P < 0.0001) with subset-directed long-term valacyclovir and/or valganciclovir therapy.
-  Secondary endpoints (cardiac, immunologic, and neurocognitive abnormalities) improved or disappeared.

• Group B CFS patients (herpesvirus plus coinfections) continued to have CFS.
So maybe...maybe...if you get rid of the coinfections before you give the drug, Group B people will recover as well?? Don't know, will have to read the full paper tomorrow.

Plus, a new study at Stanford. Granted you have to live in the bay area to do this, but they test for XMRV among many other things in an extensive blood panel. And you have to have the energy to actually go there...a bit of a self-selecting, biased sample I'd say ;)


Lee Lee said...

This was actually a good study. I believe that they were working with over 7000 blood samples so the results would definatly be reliable. Of course if you don't have herpesvirus 6 in your system then this is of no help anyway. I got re-tested this week and I'm negative for HV-6.

DolceVita said...

Yeah, it's a very thorough study! But actually, they looked at all subsets of herpesviruse (Epstein–Barr virus (EBV), cytomegalovirus (HCMV), and human herpesvirus 6 (HHV6)). They used two separate drugs, one for EBV and one for HCMV/HHV6 and said that both sets of people performed equally well. Granted, if you have NONE of the 3 above, it's still pretty useless!